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===Conversion between Attenuation and Bone Density=== <pre> BMD_value = mu-value * slope + intercept mu-value = (BMD_value โ intercept) / slope pixel_Scanco = scaling_factor * (BMD_value โ intercept) / slope </pre> For example, to convert mu_value of 1.7923 (1/cm) to BMD (mg HA/ccm): <pre> BMD_value = 1.7923 * 3.67162994e+02 + -2.06399002e+02 = 451.667 (mg HA/ccm) </pre> For example, to convert the lower threshold of 125 mg HA/ccm that is in the IPL script to pixel intensity in Scanco images: <pre> pixel_Scanco = 4096 * (125 - -2.06399002e+02) / 3.67162994e+02 = 3697 </pre> *You could get the scaling_factor, intercept and slope values from the AIM header of your scan by using aix -l command: [[File:Aix.JPG|400px]] *Reference: [[Media:Jbmr.141.pdf|Bouxsein ML, Boyd SK, Christiansen BA, Guldberg RE, Jepsen KJ, Mรผller R, Guidelines for assessment of bone microstructure in rodents using micro-computed tomography. J Bone Miner Res. 25(7): 1468-86. 2010.]] [[Image:Redirect.jpg|15px]] [[#top|''Return to Contents'']] or [[Main_Page|''Return to Main Page'']]
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